Many issues arise while developing a new drug molecule in dissolution, absorption, and bioavailability. As a result, formulation scientists are concentrating their efforts on developing formulations that will improve the efficacy of existing drugs. One such novel approach is oral dispersible films.
The advantages of oral strips and films are numerous. In the current stage of the drug delivery scenario, the significant developments revolve around the delivery system—the major benefits of first-pass metabolism, rapid onset, etc.
The oral drug delivery system (OST)
Many research groups have recently concentrated their efforts on this technology. Oral Strip Technology (OST) is gaining popularity as an oral drug delivery system. OST benefits include administration to paediatric and geriatric patient populations, which eliminates the difficulty of swallowing larger oral dosage forms.
This technology has been used for local action products, rapid release products, and the systems retained in the oral cavity to release drugs in a controlled manner. It provides an alternative platform for molecules that undergo first-pass metabolism and peptide delivery.
An ideal OST should have the following characteristics:
- high stability,
- transportability,
- ease of handling and administration,
- no unique packaging material and processing requirements,
- no water is required for application,
- and a pleasant flavour.
All of these requirements are met by oral strips. The OST is a valuable tool for increasing the patent life of existing molecules or products through product life cycle management. These dissolvable strips are used for a variety of purposes. There is a power strip, and acne strip, a cough strip, and a tooth whitening strip, to name a few. Many pharmaceutical companies are now developing strips to make it easier to deliver drugs and medicine to people. There are numerous reasons why a person might prefer dissolvable strips over traditional pills. The following are some of the benefits of dissolvable strips over medical drugs:
Also Read – The Utility of Mouth Dissolving Strips
Why is the system better?
- Oral consumption is one of the quickest and easiest ways to affect hemp-based products immediately. Water is soluble in an oral strip since it is made of a fragile ” paper layer.” As a result, the incredible plant benefits packed into the small strip are absorbed sublingually into your bloodstream.
- Oral strips dissolve instantly when they come into contact with water or saliva instead of eating something and waiting for it to pass through the digestive system. Because the active ingredients are absorbed so quickly, the beneficial effects are felt almost immediately. Not to mention that your breath now smells fantastic!
- Using mouth dissolving strips instead of pills or injections is a safe and convenient way to take any supplement. This is relatively new in India and is revolutionary for the pharmaceutical and supplement industries. Learn about dissolvable strips and their benefits, as well as why they should be preferred over traditional pills.
- Continuous research and innovation are used to improve the well-being of individuals while providing as much convenience as possible. People are spending money on various items such as the best vitamins for energy, caffeine supplements, pre-workout drinks, fat loss supplements, hair, skin, and nails supplements, and so on to feel pleasing and look good and maintain a healthy lifestyle.
- No Choking: Although pills have been the primary method of taking medications for centuries, some complications are associated with them. Some people find it difficult to swallow pills. There have also been reports of people choking on the pills. Dissolvable strips are a safer and more convenient option in these situations.
- Oral strips can improve the onset of action, lower dosage, and enhance the efficacy and safety profile of the medication. All tablet dosage forms, soft gels, and liquid formulations enter the bloodstream primarily through the gastrointestinal tract. They are degraded by stomach acid, bile, digestive enzymes, and other first-pass effects. As a result, such formulations frequently necessitate higher doses and have a delayed onset of action.
- There is no need for a person to drink water after using a dissolvable strip. As a result, you can easily consume it while on the go.
- Dose accuracy: When consuming medicine through a syrup, the accuracy of consuming the required dose is higher in oral strips.
- Compliance: Because administering medicine via strips is convenient and straightforward; patients are more likely to comply and take their medications on time.
Masking the Taste: When applied, the strips dissolve quickly. As a result, you won’t have to put up with the taste for much longer. Buccal and sublingual thin-film drug delivery, on the other hand, can avoid these issues and result in faster onsets of action at lower doses.
Other benefits of the oral strips include: being more stable, durable, and dissolving faster than other conventional dosage forms:
- Because each strip is manufactured to contain a precise amount of the drug, it allows for improved dosing accuracy compared to liquid formulations.
- Because of the intuitive nature of the dosage form and its inherent ease of administration, thin-film not only ensures more accurate drug administration but can also improve compliance. These properties are especially beneficial for patients suffering from paediatric, geriatric, and neurodegenerative diseases, where proper and complete dosing can be challenging.
- The ability of oral strips to dissolve quickly without water provides an alternative for patients with swallowing disorders and nausea, such as those receiving chemotherapy.
- The best option is to maintain the balance of bacteria in the mouth. Our mouths contain millions of “good” and “bad” bacteria that constantly collaborate to maintain a delicate balance. The “bad” bacteria cause plaque, bad breath, and tooth decay in our mouths. The “good” bacteria assist us in salivating, tasting, and removing the “bad” bacteria. This bacterial equilibrium helps to maintain your oral health.
- Thin-film drug delivery can enable the development of sensitive drug targets that would otherwise be impossible to develop in tablet or liquid formulations.
If you’ve been looking for the best way of nutritional benefits for your lifestyle, oral Strips could be the answer. Conveniently packaged, easily storable, delicious, and, most importantly, effective. They provide reliable, fast-acting relief with these strips.